Seth MacFarlane is not Jewish. The comedian, actor and creator of Family Guy is a self-avowed non-religious atheist.
Born Seth Woodbury MacFarlane on October 26, 1973 in Kent, Connecticut, to Ann Perry (née Sager, 1947-2010) and Ronald Milton MacFarlane (1946- ). MacFarlane is an actor, voice actor, animator, screenwriter, comedian, producer, director and singer. In addition to Family Guy, he has also created American Dad!, The Cleveland Show, and the movie Ted.