Page was born Clara Ann Fowler in Oklahoma. She was born into a large and poor family. Her father, B.A. Fowler, worked on the MKT railroad and her mother, Margaret, and older sisters picked cotton. She was raised in Foraker, Hardy, Muskogee and Avant, Oklahoma, before attending Daniel Webster High School in Tulsa, from which she graduated in 1945.
Page's success began in 1948 and in 1950 she released Tennessee Waltz, her most popular and best-selling single. Page appeared on The Ed Sullivan Show 18 times and in one appearance, performed Eli, Eli, an emotional Jewish ballad. Sullivan was so moved by her performance that he stumbled over his words while praising Page, saying he was so moved by this "act," rather than saying by this "song."
Page died on January 1, 2013.